Differential analysis of genome-wide methylation and gene expression in mesenchymal stem cells of patients with fractures and osteoarthritis

A Del Real, FM Pérez-Campo, AF Fernández… - Epigenetics, 2017 - Taylor & Francis
… of hMSCs in the pathogenesis of osteoporosis is still unclear. … data about the methylation
signature of skeletal hMSCs. … from fracture patients shows differentially methylated regions in …

[HTML][HTML] DNA methylation signatures of bone metabolism in osteoporosis and osteoarthritis aging-related diseases: an updated review

VV Visconti, I Cariati, S Fittipaldi, R Iundusi… - International Journal of …, 2021 - mdpi.com
… , previously identified by a genome-wide association study as a novel … bone biopsies from
postmenopausal OP women, revealing … However, these differentially methylated regions of the …

Genomewide DNA methylation study identifies significant epigenomic changes in osteoarthritic subchondral bone and similarity to overlying cartilage

MA Jeffries, M Donica, LW Baker… - Arthritis & …, 2016 - Wiley Online Library
… with hip osteoarthritis (OA) and to compare these with DNA … In subchondral bone, we
identified differential methylation of … In the present study, the degree of osteoporosis in the …

[HTML][HTML] Relationship between osteoporosis and osteoarthritis based on DNA methylation

Y Li, B Xie, Z Jiang, B Yuan - International journal of clinical and …, 2019 - ncbi.nlm.nih.gov
… [23] studied the genome-wide methylation profile of the bones in patients with hip … genome-wide
methylation analysis of bone samples revealed the regions with differential methylation

[HTML][HTML] Genome-wide DNA methylation profiling of articular cartilage reveals significant epigenetic alterations in Kashin-Beck disease and osteoarthritis

W Wang, Y Yu, J Hao, Y Wen, J Han, W Hou… - Osteoarthritis and …, 2017 - Elsevier
… We excluded the subjects with genetic bone and … a genome-wide DNA methylation profiling
of KBD, OA and normal knee cartilage, and identified a group of differentially methylated key …

[HTML][HTML] Effect of DNA methylation on gene transcription is associated with the distribution of methylation sites across the genome in osteoarthritis

P Yi, X Xu, J Yao, B Qiu - … and Therapeutic Medicine, 2021 - spandidos-publications.com
… analysis package was used to identify differentially methylated … in the impediment of
postmenopausal osteoporosis (41). … the conventional genome-wide DNA methylation analysis, …

Alterations in DNA methylation profiles in cancellous bone of postmenopausal women with osteoporosis

Y Zhou, L Yang, H Wang, X Chen, W Jiang… - FEBS Open …, 2020 - Wiley Online Library
… of patients with osteoarthritis revealed differential methylation. In view of the … bone in bone
development, we examined genome-wide DNA methylation profiles in the cancellous bone

[HTML][HTML] Genome-wide differential methylation profiles from two terpene-rich medicinal plant extracts administered in osteoarthritis rats

Y Shin, S Subramaniyam, JM Chun, JH Jeon, JM Hong… - Plants, 2021 - mdpi.com
… medicine to treat osteoarthritis and other bone diseases—were … -related diseases, such as
OA and osteoporosis [11,12]. … shows that 929 genes contained CpGs from all three regions. …

[HTML][HTML] Identification of DNA methylation changes associated with disease progression in subchondral bone with site-matched cartilage in knee osteoarthritis

Y Zhang, N Fukui, M Yahata, Y Katsuragawa… - Scientific Reports, 2016 - nature.com
genome-wide DNA methylation profiles in subchondral bone and identify the differential
methylated genes (… GO analysis of the 41 shared DMGs revealed higher enrichment folds in the …

Genomewide DNA methylation profile analysis in thoracic ossification of the ligamentum flavum

T Fan, X Meng, C Sun, X Yang, G Chen… - Journal of Cellular …, 2020 - Wiley Online Library
… , such as ankylosing spondylitis (AS), osteoporosis and osteoarthritis, show abnormal DNA
… shortlisted the differentially methylated GO terms functionally related to bone development, …